Equipe de recherche Addict'Aide : Laurence Lalanne

Présentation en quelques mots (parcours, compétences…) :

Professeur des universités-Patricien Hospitalier de Psychiatrie et Addictologie

Chercheur Unité INSERM 1114, thème de recherche : Etude des mécanismes physiopathologiques cognitifs des troubles addictifs chez l’homme.

Formée à la recherche chez l’animal : Postdoc à l’IGBMC en 2013-2014, laboratoire du Professeur Brigitte Kieffer

Université : de Strasbourg

Spécialité : Neurosciences, addictologie, psychiatrie

Travaux réalisés (sélection d’articles)

  1. Giersch A, Lalanne L, Corves C, Seubert J, Shi Z, Foucher J, Elliott MA.  Extended visual simultaneity thresholds in patients with schizophrenia. Schizophr Bull. 2009 Jul;35(4):816-25. doi: 10.1093/schbul/sbn016. (IF 7.467, rang A)
  2. Lalanne L, van Assche M, Giersch A. When Predictive Mechanisms Go Wrong: Disordered Visual Synchrony Thresholds in Schizophrenia. Schizophr Bull. 2012 May;38(3):506-13. doi: 10.1093/schbul/sbq107. (IF 8.486, rang A)
  3. Lalanne L, Dufour A, Giersch A: Attention and Masking in Schizophrenia. Biol Psychiatry. 2012 Jan 15;71(2):162-8. doi: 10.1016/j.biopsych.2011.09.018. (IF 9.247, rang A)
  4. Ayranci G, Befort K, Lalanne L, Kieffer B, Lutz PE. Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains. Psychopharmacology (Berl). 2015 Jun;232(11):1957-71. doi: 10.1007/s00213-014-3826-5. (IF 3.54, rang B)
  5. Lalanne L, Ayranci G, Filliol D, Befort K, Glaveriaux C, Kieffer BL, Lutz PE. Kappa opioid receptor antagonism and chronic antidepressant treatment have beneficial activities on social interactions and grooming deficits during heroin abstinence. Addict Biol. 2017 Jul;22(4):1010-1021. doi: 10.1111/adb.12392. (IF 4.547, rang B
  6. Schwitzer T, Schwan R, Albuisson E, Giersch A, Ingster-Moati I, Lalanne L, CAUSA MAP study group, Angioi-Duprez K, Laprevote V. Association Between Regular Cannabis Use and Ganglion Cell Dysfunction. JAMA Ophthalmol. 2017 Jan 1;135(1):54-60. doi: 10.1001/jamaophthalmol.2016.4761. (IF 5.625, rang A)
  7. Lalanne L, Ferrand-Devouge E, Kirchherr S, Rauch L, Koning E, Speeg C, Laprevote V, Giersch A. Impaired contrast sensitivity at low spatial frequency in cannabis users with early onset. Eur Neuropsychopharmacol. 2017 Dec;27(12):1289-1297. doi: 10.1016/j.euroneuro.2017.09.006. (IF 4.239, rang B)
  8. Schwitzer T, Schwan R, Angioi-Duprez K, Giersch A, Lalanne L, Albuisson E, Laprevote V. Delayed bipolar and ganglion cells neuroretinal processing in regular cannabis users: The retina as a relevant site to investigate brain synaptic transmission dysfunctions.J Psychiatr Res. 2018 Aug;103:75-82. doi: 10.1016/j.jpsychires.2018.04.021. (IF 4, Rang B)
  9. Schwitzer T, Henrion ML, Sarre D, Albuisson E, Angioi-Duprez K, Giersch A, Lalanne L, Schwan R, Laprevote V. Spatial localization of retinal anomalies in regular cannabis users: The relevance of the multifocal electroretinogram.Schizophr Res. 2019 Jan 26. pii: S0920-9964(19)30013-1. doi: 10.1016/j.schres.2019.01.013. (IF 3.958, Rang B)
  10. Auriacombe M, Roux P, Briand Madrid L, Kirchherr S, Kervran C, Chauvin C, Gutowski M, Denis C, Carrieri MP, Lalanne L, Jauffret-Roustide M; and the Cosinus study group. Impact of drug consumption rooms on risk practices and access to care in people who inject drugs in France: the COSINUS prospective cohort study protocol. BMJ Open. 2019 Feb 21;9(2):e023683. doi: 10.1136/bmjopen-2018-023683. (IF 2.413, Rang C).
  11. Paasche C, Weibel S, Wittmann M, Lalanne L.Time perception and impulsivity: A proposed relationship in addictive disorders.Neurosci Biobehav Rev. 2018 Dec 6. pii: S0149-7634(18)30034-4. doi: 10.1016/j.neubiorev.2018.12.006. (IF 8.037, Rang A)
  12. Schwitzer T, Schwan R, Angioi-Duprez K, Lalanne L, Giersch A, Laprevote V. Cannabis use and human retina: The path for the study of brain synaptic transmission dysfunctions in cannabis users. Neurosci Biobehav Rev. 2019 Feb 14. pii: S0149-7634(18)30331-2. doi: 10.1016/j.neubiorev.2018.12.001. (IF 8.037, Rang A)
  13. Massotte D, Lalanne-Tongio L, Befort K. Addiction: A neurobiological and cognitive brain disorder. Neurosci Biobehav Rev. 2019 Jul 29. pii: S0149-7634(19)30628-1. doi: 10.1016/j.neubiorev.2019.07.012.
  14. Belzeaux R*, Lalanne L*, Kieffer B, Lutz PE. Focusing on the opioid system for addiction biomarker discovery. Trends Mol Med. 2018 Feb;24(2):206-220. doi: 10.1016/j.molmed.2017.12.004. (IF: 10.732, IFP 10.732, rang A) *equal contribution